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Severe gastrointestinal conditions: Those with delayed gastric emptying, gastroparesis, or chronic GI dysmotility may experience exacerbated symptoms due to the drugs action on gastric motility

Therefore, EGCG can be esterified with long-chain saturated fatty acids and unsaturated fatty acids, and the structure can be modified to ultimately produce the lipated EGCG derivatives

Hoque TS, Hossain MA, Mostofa MG, Burritt DJ, Fujita M, Tran LSP (2016) Methylglyoxal: an emerging signaling molecule in plant abiotic stress responses and tolerance

The methodological quality of individual trials was also assessed according to a) whether randomization was concealed, b) blinding, c) analysis was based on the intention-to-treat (ITT) principle, d) patient selection, e) comparability of groups at baseline, f) extent of follow-up, g) description of treatment protocol and co-interventions, and h) definition of clinical outcomes

A: Always consult with your healthcare provider before combining any supplements or alternative therapies with your current medication

doi: 10.1038/s41586-018-0449-8 30 RodgersJTKingKYBrettJOCromieMJCharvilleGWMaguireKKet al