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However, the altered tissue microenvironment characteristic of chronic metabolic and inflammatory diseases significantly impairs neutrophil function, resulting in aberrant responses and tissue damage

Animal model studies have preliminarily revealed that Clostridium colonization can curtail the overgrowth of pro-inflammatory microbiota, restore the intestinal mucosal barrier, and limit systemic translocation of bacterial LPS, ultimately reestablishing gut microbial homeostasis (206, 207)

The latest data show that approximately 15% of reproductive couples in the world have a problem with infertility (2)

The main hormones involved are estrogen and progesterone, which are present in various forms of hormonal contraceptives such as birth control pills, patches, and rings

The mice were randomly divided into four groups (each containing at least five mice): a natural aging group, a natural aging + FOXO4-DRI group, a D-Gal group, and a D-Gal + FOXO4-DRI group

A key study investigating coagulation factors employed a two-sample Mendelian randomization (MR) approach using large-scale genome-wide association study (GWAS) summary statistics from the UK Biobank (4354 cases, 217,500 controls) and FinnGen (8288 cases, 68,969 controls) cohorts to explore causal associations between 11 coagulation factors and endometriosis risk