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Knocking down any component of the Dcaf11 complex attenuates the ubiquitination level of p21, inhibiting osteosarcoma cell proliferation

Anaphylactic shock is the most serious adverse effect

Strategies aimed at modulating the labile iron pool, enhancing GPX4 activity, or using ferroptosis inhibitors may provide novel means to mitigate ischemia-reperfusion injury and improve graft outcomes