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However, it is not associated with overall survival (Kunzmann et al., 2013)

(A) Invasion capability of AR Huh-BAT cells significantly suppressed by BSO (200 M), 3-BP (20 M) and a combination by invasion assay using Boyden chambers (quantified at right panels)

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What can be said is that the triple-agonist mechanism appears to produce a steeper dose-response curve than either the dual-agonist (tirzepatide) or single-agonist (semaglutide) approach