foxo4-dri senolytic or senomorphic Targeting cellular senescence with senotherapeutics: senolytics and senomorphics - Zhang - 2023 - The FEBS Journal CHK2-USP37 axis stabilizes FOXO4 to
CHK2 USP37 axis stabilizes FOXO4 to sustain senescence and evade apoptosis PNAS Molecular modelling of the FOXO4 TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells ScienceDirect FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway PMC Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging PMC The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Targeting Cellular Senescence in Aging and Age Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies
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