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or in patients with chronic bronchitis where treatment periods were lengthy (1224 weeks) at doses of 400600 mg/day where NAC reduced the risk of exacerbations and improves symptoms in patients with chronic bronchitis compared with placebo (11 trials, 2,011 participants).(7) Clinical trial evidence for the use of NAC as an antioxidant in influenza and other acute viral respiratory tract infections is limited and relate to isolated small clinical trials

Nutr Metab Cardiovasc Dis 20(1):7277 Ogawa D, Asanuma M, Miyazaki I, Tachibana H, Wada J, Sogawa N, Sugaya T, Kitamura S, Maeshima Y, Shikata K (2011) High glucose increases metallothionein expression in renal proximal tubular epithelial cells

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Cellular susceptibility to ferroptosis is therefore governed by pathways controlling lipid metabolism, iron homeostasis, and redox balance

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Phagocytosis of A and secretion of A-degrading enzymes by astrocytes near A plaques (Yamaguchi et al., 1998