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The combination results in the highest CAT activity among treatments (0.931 0.025), reflecting synergistic protection against oxidative stress

These effects occur through mechanisms including enhanced angiogenesis, modulation of growth factor expression, and direct cytoprotection of gastric epithelial cells

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Role of ROS in development of microvascular complications The microvascular complications of diabetes, including nephropathy, retinopathy and neuropathy, are common manifestations of diabetes

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10.1016/j.ijpharm.2022.122570 98 KhoshnamS