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In neurodegenerative diseases, microglia transition from a ramified resting state to an activated state characterized by amoeboid morphology, proliferative expansion, and secretion of inflammatory mediators (101)

Loss of PRMT7 in the heart reduces symmetrical dimethylation of -catenin, enhances Wnt--catenin signaling, and promotes myocardial hypertrophy

These metabolic shifts are thought to play a role in improved energy turnover and lipid utilization in adipose tissue

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International anesthesiology clinics 45(2):27 Peprah K, Severn M (2020) Intranasal and intramuscular naloxone for opioid overdose in the pre-hospital setting: a review of comparative clinical and cost-effectiveness, and guidelines Georgiou NA, van der Bruggen T, Oudshoorn M, Nottet HS, Marx JJ, van Asbeck BS (2000) Inhibition of human immunodeficiency virus type 1 replication in human mononuclear blood cells by the iron chelators deferoxamine, deferiprone, and bleomycin