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The Institute of Medicine reports that no adverse effects have been associated with excess vitamin B12 intake from food and supplements in healthy individuals. However, if youre not deficient in vitamin B12 to begin with or you dont address the underlying reasons you might be deficient, injections likely wont do much to improve overall quality of life

There have been reported cases of permanent injury to extraocular muscles requiring surgical repair following retrobulbar administration

B12 Injections Vitamin B12 injections are commonly used to address B12 deficiency, which can contribute to fatigue, weakness, and neurological issues

MIC B12 Benefits and B12 With MIC Benefits: Whats Plausible vs Proven Energy and Fatigue Best-supported scenario: If you have vitamin B12 deficiency, replacing B12 can improve deficiency-related symptoms (NIH ODS provides an overview in its Vitamin B12 fact sheet )

Low red blood cell counts may indicate deficiency

In those who have trouble absorbing the vitamin through dietary sources or supplements, vitamin B12 injections are beneficial in restoring a deficit