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Often, yes

2006, doi: 10.1007/s12603-006-0009-7

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8f) and compared to Pri-PCa, we observed that the AR + BCL-2 - PCa cells represented the majority in primary tumors whereas in CRPC the AR - BCL-2 + cells became the predominant cell population accompanied by increased AR + BCL-2 + and AR - BCL-2 - cells (Fig