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The clinical evaluation before prescribing exists precisely to identify these contraindications

For adults, the cutoff for serum holoTC, based on the relation of holoTC to serum methylmalonic acid, is 12 mol/L), the association of total serum B12 levels with serum MMA (and tHcy) was explored with restricted cubic splines (Figure 22b.5)

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As its responsible for energy production, it could ease the fatigue associated with it

Verapamil Verapamil, a non-dihydropyridine Class IV calcium channel blocker, slows conduction through the AV node and reduces myocardial contractility due to its adverse inotropic effect (11)(49)(50)

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