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10.1016/j.clnu.2018.08.032 148 WilliamsP

In contrast, zVAD had a minimal effect on ibrutinib-induced cell death, suggesting that apoptosis plays only a minor role, whereas ferroptosis contributes more prominently to the cytotoxic effects of ibrutinib (Fig

They are also rich sources of important phytonutrients including carotenoids, polyphenols, and glucosinolates, which include indole-3-carbinol (I3C) (derived from the breakdown of glucobrassicin found in cruciferous vegetables) and sulforaphane (an isothiocyanate derived from glucoraphanin, a glucosinolate)

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Innate and adaptive immune responses against coronavirus

Mechanistically, the inflammation mediated by the Caspase-1/NLRP3, TLR4/NLRP3, MAPK/NF-B/NLRP3, and Nrf2/HO-1/NLRP3 pathways have been implicated in the pathogenesis and progression of AP (Papantoniou et al., 2024), highlighting their potential as therapeutic targets