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B12 is a water-soluble vitamin, so any excess quickly goes out through the urine

9 , S239S243 (2020)

In living cells, the primary determinant of the cellular redox state is the GSH/GSSG ratio and the efficiency of de novo GSH biosynthesis

Murgia, X., de Souza Carvalho, C

Abnormal calcium may be related to parathyroid disorders, kidney disease, vitamin D status, certain cancers, dehydration, or medication effects

Other people may have recently had gastric band surgery or suffer from autoimmune atrophic gastritis which prevents them from absorbing B12 from their food