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10.1186/1471-2407-12-174 168 ShkoporovA

PMID: 38169320 Eur J Med Chem2022 Feb 15:230:114088

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer

CBRs may attenuate pro-inflammatory cytokine secretion by interfering with the phosphorylation of mitogen activated protein kinases (MAPK), such as extracellular signal-regulated kinase (ERK), which is known to participate in pro-inflammatory pathways, as shown in microglial cell line cultures (Eljaschewitsch et al., 2006