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Mitochondrial quality control in the heart: the balance between physiological and pathological stress

Non-enzymatic antioxidant system Inside the cell, several nucleophilic organic compounds, such as vitamin A, vitamin E, ascorbic acid, and dihydro lipoic acid, function to neutralize reactive species

Inotodiol specifically demonstrated its anti-NAFLD properties by regulating the lipid metabolism pathway, farnesoid X receptor (FXR)/small heterodimer partner (SHP)/sterol regulatory element-binding protein-1c (SREBP-1c) (Liu et al., 2016)

By contrast, the activation of CPT1 by C75 could restore both cardiac and mitochondrial FAO without any effects on inflammatory gene expression or cardiac function

(2018) 28:R350r351

The trial followed 54 healthy adults over six months, dividing them into a placebo group, a low-dose group (250 mg/day), and a high-dose group (1000 mg/day), meticulously tracking glutathione levels across multiple cellular compartments, as detailed in the published clinical trial