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Mutations in specific mtDNA or nDNA genes encoding the mitochondrial respiratory chain are closely related to epilepsy

Mechanistic insights into the role of GH and IGF-I secretion in age-related alterations in cognitive function were assessed in several preclinical studies by Sonntag and colleagues, demonstrating somatotropic effects on rodent brain aging (31)

Inhibiting heat shock protein 90 protects nucleus pulposus-derived stem/progenitor cells from compression-induced necroptosis and apoptosis (in eng)

Furthermore, it is also possible that DMSO acts as a methyl donor to induce hypermethylation 31

In contrast, 12/15-LOX has been directly implicated in ferroptosis-driven neuronal injury