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Induction of JAK2/STAT3 pathway contributes to protective effects of different therapeutics against myocardial ischemia/reperfusion

Simultaneously, research (106) on another member of the GGT family has shown that low GGT7 expression may elevate cell ROS levels, inhibiting apoptosis and fostering tumor proliferation

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Kutahyalioglu M, Nguyen HT, Kwatampora L, Clarke C, Silva A, Ibrahim E, Waguespack SG, Cabanillas ME, Jimenez C, Hu MI, Sherman SI, Kopetz S , Broaddus R, Dadu R, Wanland K, Williams M, Zafereo M, Perrier N, Busaidy NL

Zou, W., Wolchok, J

In this setting, CYB5R3 functions not only as a preserver of hemoglobin activity but also as a responsive regulatory valve controlling NO signaling within RBCs