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Together, the peptides offer a complementary platform to examine inflammation resolution, fibroblast/keratinocyte behavior, matrix deposition, and vascular support in preclinical systems

95% CI 0.560.78

S-alk(en)yl cysteines of garlic inhibit cholesterol synthesis by deactivating HMG-CoA reductase in cultured rat hepatocytes

Available from: [DOI] [PMC free article] [PubMed] [Google Scholar] 273.Lin RS, Rodriguez C, Veillette A, Lodish HF

This causes the Foxo3 protein to lose its ability to perform transcriptional functions and causes it to move from the nucleus to the cytoplasm, where it is then targeted for degradation (John et al

The peptide was originally identified as a partial sequence derived from a larger protein present in human gastric juice, first characterized by Professor Predrag Sikiric and colleagues at the University of Zagreb, Croatia, in the early 1990s