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Description

While traditional capsules are made of gelatin, which is animal-derived, vegetarian capsules are also available

Consequently, failure to convert RanGTP to RanGDP, for example, due to RanGAP depletion, is predicted to result in an accumulation of RanGTP in the cytoplasm and a shift in the ratio of nuclear to cytoplasmic total Ran protein [38]

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We use these results as a starting point to identify GAPDH as a neutrophil-intrinsic NET-suppressor mechanism and to investigate the molecular mechanisms by which GAPDH inhibition regulates neutrophil function