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Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

It plays a vital role in detoxification by neutralizing free radicals, supporting the immune system, and aiding in the regeneration of other antioxidants like vitamins C and E

In summary, AS-IV negatively regulates fibroblast fibrosis, as primarily indicated by the remarkable promotion of the dephosphorylation of Smad2 and Smad3 in fibroblasts and restoration of Smad7 activity, indicating that AS-IV mediates positive feedback inhibition and the negative feedback enhancement of the TGF-1/Smads signaling pathway (77,78)

Being an amazing antioxidant, glutathione neutralizes free radicals caused by pollution and UV rays

Produced in the liver, glutathione assists with detoxifying xenobiotics and heavy metals, neutralizes hydrogen peroxide, maintains the integrity of blood cells, and helps to transport amino acids across cell membranes

Chi square and Fisher exact tests were used to compare categorical variables, and t-test for continuous variables