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We recently documented the conserved autophagy function of AKAP11 in human neurons and demonstrated a critical role of AKAP11 in maintaining the homeostasis of PKA-RI protein complex in the soma and neurites through autophagy degradation 10

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The exogenous induction of GSH depletion causes mitochondrial-dependent apoptosis in CYP2E1-expressing HepG2 cells (E47 cells) [123]

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