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The history of medical ozone has been covered in many published articles. Its underlying mechanism is considered to be a hormetic effect: an adaptive response of cells and organisms to a moderate (usually intermittent) stress. This aim of this article is to review the latest literature effects, and observations of the novel modality for various common medical challenges

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Sun J, Patel CB, Jang T, Merchant M, Chen C, Kazerounian S, et al

Acne scars are permanent textural changes and indentations that occur on the skin as a result of severe acne

Side effects are usually mild flushing, mild nausea, or temporary stomach pressure