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In a meta-analysis study, Notarte et al

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Myeloid-specific blockade of Notch signaling attenuates choroidal neovascularization through compromised macrophage infiltration and polarization in mice

Jain N, Thompson P, Burger J, Borthakur G , Bose P, Estrov Z, Ferrajoli A, Takahashi K, Garg N, Wang X, Gandhi V, Plunkett W, Kanagal-Shamanna R, Patel K, Lopez W, Kantarjian H, O'Brien S, Keating M, Wierda W

Further investigation is imperative to comprehensively elucidate the underlying mechanism governing this interplay between necroptosis and ferroptosis in PF

Ferroptosis has been distinguished from other types of cell death, such as apoptosis, autophagic cell death and necroptosis, at the cell morphology, genetic and biochemistry levels (1)