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Blood and stool samples were collected at various time points between August 2015 to April 2024, beginning at or shortly after treatment initiation

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Antioxid Redox Signal 20 , 29072922 (2014)

56 reported that intracellular reactive oxygen species and all amino acids, including glutamine, were increased in the NH 4 Cl-treated human astrocyte

These alterations may be related to mitochondrial malfunction brought on by DOX administration

In contrast, blood glucose level of 54 mg/dL or less occurred in 6% of patients receiving the 14 mg tablets, 3% of patients receiving placebo, and 0% of patients receiving the 7 mg tablets