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One major role of iron regulation in the body is iron storage via ferritin to sequester iron away from bacteria.[ref] A 2024 study of over 140,000 Danish people found that those who carried the C282Y variant associated with hemochromatosis were at an increased risk of infection, sepsis, and death from infection

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12 However, recent studies have shown that GST also takes part in promoting multidrug resistance in p53-mutated lung cancer cells

One study demonstrated that conducting diphenyl-1-pyrenylphosphine experiments using HEK-293 cells revealed the formation of lipid hydroperoxides catalyzed by LOX (68)

10.1016/j.redox.2022.102313 Redox Biol