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Eight week old female and male mice, after anaesthetization with intraperitoneal injection of ketamine hydrochloride (100 mg/kg body weight, Thea), xylazine (10 mg/kg body weight, VMD), and the local anesthetic (Unicane 0.4%

The process takes just a few minutes, and there is no downtime, allowing you to continue your day immediately afterward

Sens Actuators B Chem 199:463469

Durham et al., 2000

Endogenous nitric oxide (NO), a proinflammatory mediator, was shown to be a critical factor in seizure initiation and to promote seizures in mice (165)

Due to the absence of typical clinical symptoms and specific biomarkers in the early stages, and more than 70% of ovarian cancer cases have progressed to an advanced stage by the time they are diagnosed