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Until the modern period, the destruction of the Temple was the most cataclysmic moment in the history of the Jewish people

Limitations of traditional target discovery methods Traditional target discovery methods primarily focus on validating single targets and screening potential drugs, often employing techniques such as high-throughput screening (HTS) and in vitro experiments [234, 235]

These hormones are precursors of estrogenes [18]

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Studies in recent years have found that dexmedetomidine, a clinical drug commonly used for sedation, plays a neuroprotective role through an anti-inflammatory mechanism (Liu et al., 2017

Mol Psychiatry (2022) 27:268999