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Data are from the on-treatment observation period (during treatment with trial product [any dose of trial medication administered within the previous 49 days (that is, any period of temporary treatment interruption with trial product was excluded))

These formulations have different affinities to key proteins and receptors which facilitate the generation of biologically active intracellular cobalamin and thus, differ in their rates of tissue retention and bioavailability (Paul and Brady, 2017)

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HGF can upregulate the transcription factor Ets-1, thus enhancing the expression of vascular endothelial growth factors (VEGFs) (Tomita et al., 2003)

Raise usable NAD by stopping NAM from being siphoned off, it feeds the NAD salvage loop, supporting mitochondrial enzymes (e.g., sirtuins)

How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test reveals predispositions in genes affecting metabolic and antioxidant pathways, including variants in SOD2 (superoxide dismutase) and GSTP1 (glutathione-S-transferase), which may influence individual antioxidant capacity