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Future trials should ideally close the gaps in evidence for the pharmacological and non-pharmacological treatment of these, still underestimated, disturbances in the specific setting of PD

The diabetes drug metformin and all the proton pump inhibitors (PPIs) such as omeprazole ( Prilosec ), esomeprazole ( Nexium ), lansoprazole ( Prevacid ) and pantoprazole ( Protonix ) can interfere with vitamin B12 absorption

Further supporting the above are the findings that low tissue copper, in itself, may increase stem cell proliferation and availability in animals

NHS treatment guidance describes a loading course followed by maintenance injections every two to three months for many people, while a diet-related deficiency may need less

Kanters S, Renaud F, Rangaraj A, Zhang K, Limbrick-Oldfield E, Hughes M et al

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