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The most extensively researched and clinically proven copper peptide is GHK-Cu, a tripeptide composed of glycine, L-histidine, and L-lysine bound to copper

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A toxicity study in rats administered oral GABA (500-2500 mg/kg/day) for 13 weeks and found no significant abnormalities in behavior, weight gain, or blood indices including general chemistries, glucose, renal function, hematology and liver function