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One day after the addition of growth hormone to the BPC 157-treated tendon fibroblasts, cells were washed once with 1xPBS, followed by adding 1 mL DMEM containing 0.05 mg/mL 3-[4,5-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide (MTT)

Notably, traditional compounds used for treating other diseases should be reevaluated to determine whether they work in tumors expressing mutant p53

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Within the liver, hepatocytes subjected to lipid overload and lipotoxic stress release damage-associated molecular patterns (DAMPs), which activate resident immune cells such as Kupffer cells, leading to the secretion of pro-inflammatory cytokines, including TNF-, IL-1, and IL-6

Furthermore, BPC157 positively influenced muscle metabolism, correcting deranged muscle proliferation and myogenesis, as shown by changes in FoxO3a, p-AKT, p-mTOR, and P-GSK-3 expression

and co-wrote the manuscript