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Analysis of adult mouse brain tissue revealed that OPC differentiation was widespread and remarkably consistent between brain regions that will ultimately contain different amounts of myelin

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The methods for determining the level of a marker according to the diagnostic method of the invention will depend of the type or marker, namely, lipids, polar metabolites or genes

Similarly, mutations in Chk2 , which encodes a kinase downstream of ATM in the ATM/Chk2/p53 pathway, have been reported to contribute to radioresistance in gliomas [64]

This therapeutic strategy holds significant translational promise for neurodegenerative diseases such as AD, ALS, and PD [128, 360]

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