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Drug Metab Dispos 46(7):10011013

We then overexpressed GCLC in cells with ACTL6A knocked down and found that GCLC reversed the inhibition of cell proliferation (Fig

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Interestingly, no sexual dimorphism in GR transcript variants was found in CBMCs from preterm/term neonates (237240, 250), further emphasizing glucocorticoid tissue-specific effects

Overall, T cell activation leads to upregulation of the GSH pathway to prevent excessive ROS accumulation, ensuring the activation of mTOR and NFAT, and facilitating proper T cell metabolic reprogramming and cell fate decisions

Candida albicans stimulates arachidonic acid liberation from alveolar macrophages through alpha-mannan and beta-glucan cell wall components