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Then FITC solution was added dropwise into laccase (5 mg/mL) solution, and the mixed solution was stirred at 4 C for 4 h

(35076955) (Chlorpromazine is a moderate inhibitor with a Ki value of perhaps ~800 nM

doi: 10.1111/j.1469-1809.2012.00705.x 114 ShiM.CaoL.LiuH.ZhouY.ZhaoY.XiaY

Rastegari et al., 2019

Hence, a step-by-step, multimodal approach, which includes a mix of treatments and procedures targeting the melanin synthesis pathways, the anti-inflammatory environment, senescence and vascularity, should be used, along with avoidance of exacerbating factors such as UV light and hormonal contraception (Figure 3)