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Those who started on a placebo and switched to Kesimpta in the extension trial also experienced pronounced reductions in their relapse rates and MRI lesions, and their NEDA-3 rates increased after switching as well

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Given this clinical history and the mode of inheritance of clEDS, a diagnosis of clEDS is likely, though unproven

Further studies investigating PBDE exposure at the placenta-fetal brain interface and its ability to induce cellular level changes associated with autism spectrum disorders will be evaluated