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In general, according to the results of various studies, it seems that cyclic ACPs have better anti-cancer and less toxicity than other ACPs

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O., Silva, F., Gouveia-Fernandes, S

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Orgotein was the first Cu,Zn-SOD mimetic drug developed in 1971

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Sun Q-A, Kirnarsky L, Sherman S, Gladyshev VN (2001) Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems

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