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10.1016/j.cmet.2013.06.015 Cell Metab

This metabolic shift changes mitochondrial ratios of acetyl-CoA and nicotinamide adenine dinucleotide (NAD+)/nicotinamide adenine dinucleotide + hydrogen (NADH), positively impacting the redox state of cells [6, 9], and limiting seizure activity [10]

The name and homology details of AIFM2 indicate how it was identified by its function to induce apoptosis by releasing cytochrome c and caspase 9 (Miriyala et al., 2016)