This medium was then replaced with matched medium with glycine substituted for 0.4 mM 13 C 2 15 N 1 -glycine for 1 h before metabolite extraction
Researchers call MOTS-c a metabolism peptide since it has a profound impact on how cells handle nutrients and energy
[275] designed 2 lipid NPs, namely chondroitin sulfate-modified vismodegib-loaded NPs (CS-NPs/VDG) and glycyrrhetinic acid-modified silybin-loaded NPs (GA-NPs/SIB), which can target the repair of LSECs, inhibition of HSCs, and restoration of hepatocyte function, ultimately reversing liver fibrosis by regulating lipid oxidation and metabolic pathways
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doi: 10.3389/fphar.2019.01614 105 GudurRABhosaleSJGudurAKDatkhileKD
