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More than two thirds of the B 12 excreted in bile is reabsorbed in the small intestine, but this reabsorption is reduced in people with pernicious anaemia or other causes of B 12 malabsorption.5859 Nitrous oxide toxicity The Association of British Neurologists has recently issued guidance on recognising and managing nitrous oxide toxicity associated with B 12 deficiency.14 It recommends rapid initiation of alternate-day intramuscular hydroxocobalamin therapy, and maintenance of this treatment until all symptoms have resolved or there is no further neurological improvement, with long term B 12 therapy depending on the presence of deficiency on presentation, together with total abstinence from the use of nitrous oxide

Government guidelines for GP in support of patients if you find it difficult/impossible to change brands gov.uk/drug-safety-update/l

Some functions that choline serves in the body are: Production of sphingomyelin and phosphatidylcholine, which are needed to maintain cell membrane integrity

Why does injection depth into the muscle belly matter

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But, their effects are not just at the injection site