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Interestingly, type I IFN targets also human neutrophils, for instance by prolonging their survival 16 , or by inducing the expression of CXCL10 mRNA 17 and the production of biologically active TNF-related apoptosis-inducing ligand (TRAIL) 18

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The relatively slower growth rate and lower growth yield of the wild-type and ghd3 / gdh3 strains on proline or arginine medium, compared to MM medium, can be explained by the fact that amino acids are poor carbon and nitrogen sources in comparison to the glucose and ammonia present in MM medium