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Discrimination between the ionic and osmotic components of salt stress in relation to free polyamine level in rice ( Oryza sativa )

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DOI: 10.7554/eLife.13378 Liu, W., Struik, D., Nies, V.J., Jurdzinski, A., Harkema, L., de Bruin, A., Verkade, H.J., Downes, M., Evans, R.M., van Zutphen, T., Jonker, J.W

It has been demonstrated that xCT deficiency or inhibition suppresses cell proliferation and tumor growth and induces cell death by apoptosis or cell death mediated by accumulation of lipid ROS or lipid peroxidation, known as ferroptosis (231234)

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After SCI in mice, we detected a rapid and sustained reduction of system xCT an antiporter required to transport cystine into cells for the production of GSH