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reduced production of short-chain fatty acids and B-Vitamins) [14] [15] [16] [17] [18] and a process referred to as cellular senescence and the senescence-associated secretory phenotype in the pathogenesis of PSC

Thus, in general, chemotherapy mainly remains an option for palliative treatment in cats with non-resectable FISS, when radiation therapy is not available (Zabielska-Koczyws et al., 2017)