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doi: 10.1126/science.1198469 90 ReadSMalmstrmVPowrieF

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Works on reducing fine lines

A further disadvantage of ingesting L-Arginine directly is that it is metabolized in the liver by arginase in men with heart disease, arginase is upregulated or more active meaning that more Arginine is converted to the amino acid ornithine, which can potentially lead to herpes outbreaks and other issues