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In an amyotrophic lateral sclerosis (ALS) mouse model (SOD1 G93A ), the administration of KD was able to promote ATP synthesis by bypassing the inhibited complex I in the mitochondrial respiratory chain, increasing mitochondrial energy production and membrane stabilization, leading to increased motor neuron survival and improved motor function compared to normally fed mice

10.1016/j.copbio.2006.06.003 Curr

52 Proteases are involved in tissue remodelling, inflammation and degradation of the extracellular matrix (ECM) components and the pathology of COPD

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doi: 10.1245/s10434-013-3088-1 53 FarrerasNArtigasVCardonaDRiusXTriasMGonzlezJA