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found that targeting cGAS and inhibiting lactylation modifications can promote the transition of microglia from the M1 phenotype to a repair phenotype [110], the addition of lactate has no effect on the expression of A2 astrocytes and only weakens M1 polarization process [57]

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Eur J Cardiovasc Prev Rehabil

This allosteric targeting approach can effectively avoid pseudotargeting or loss of target, and the plug-and-play targeting moieties effectively improved the biocompatibility and stability of the formulation and showed good universality for various lipid-based carriers and membrane receptors

The role of thioredoxin reductase 1 in melanoma metabolism and metastasis

The only available selective beta-blocker medication is betaxolol (Betoptic, Betoptic S)