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Role of iron, glutathione and lipid peroxidation in ferroptosis. Arrows Download Scientific Diagram The role of glutathione peroxidase 4 in neuronal ferroptosis and its therapeutic potential in ischemic and hemorrhagic stroke ScienceDirect Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis PMC Selective Small Molecule Activator of Patient Derived GPX4 Variant ACS Chemical Biology Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. Revisiting the role of iron in ferroptosis

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