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These results suggest that the brains of patients with ALS have limited antioxidant capacity [180]

PMID: 75 RatajczakAESzymczak-TomczakASkrzypczak-ZieliskaMRychterAMZawadaADobrowolskaAet al

Thats because dying itself is a journey into another outfit so to speak

An increase in pH would be expected to decrease the lysosomal degradation capability since acidic pH is optimal for lysosome enzyme activity

The combined inhibition of endogenous serine synthesis and restriction of exogenous serine/glycine significantly overcomes Np63-mediated carboplatin resistance