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[DOI] [PubMed] [Google Scholar] Hauser ER, Finkelstein JE, Valle D, Brusilow SW

The administration of acetyl-l-carnitine prevented atherosclerosis onset in Wistar rats by blocking the expression of oxidative-stress-related genes, controlling inflammation parameters, and regulating blood lipids, as well as displaying myocardial protection and acting against atherosclerotic cardiovascular disease, by reducing mRNA levels, iNOS, IL-1b, TNF-a and CPR protein in the hearts and aortas of rats with induced atherosclerosis [82]