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Dosing changes when kidney function is low Because the kidneys clear many substances, standard dosing may not apply when your eGFR is reduced

A growing hypothesis proposes that drug tolerance and persistence may precede and facilitate the development of stable resistance, as observed in bacterial pathogens

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Norus T, Fode M and Nordling J: Ileal conduit without cystectomy may be an appropriate option in the treatment of intractable bladder pain syndrome/interstitial cystitis

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