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10.3390/ijms22095010 12 AstutiI.Ysrafil (2020)

Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease." N Engl J Med (2007) 356:775-89

BMJ 338 , b725 (2009)

In addition, a significant reduction in the activities of SOD, CAT and TAC, and increase in the level of NO and MDA in patients treated with anti-epileptic drugs compared to untreated patients suggest the induction of additional OS, utilization of antioxidant enzymes and reduction of the antioxidant capacity, which implicate as seizure recurrence and drug unresponsiveness